ADH has two actions, one on the kidney and the other on vascular smooth muscle, these actions are mediated by different receptors, different intracellular mechanisms, and different secondary messengers.

a. The major action of ADH is to increase the water permeability of principal cells in the late distal tubule and collecting duct.

b. The receptor for ADH on the principal cells is a V2 receptor, which is coupled to adenylyl cyclase via a Gs protein. 

c. The second messenger is cAMP, via phosphorylation steps, directs the insertion of water channels, aquaporin 2 (AQP2), in luminal membranes.

d. The receptor for ADH on the principal cells is a V1 receptor, which is coupled to phospholipase C via Gq protein.

Which one of the following combination of above statements is correct?

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#Question id: 33355

#Unit 1. Molecules and their Interaction Relevant to Biology

Which statement stands incorrect

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#Question id: 11369

#Unit 9. Diversity of Life Forms

If new genetic variation in the experimental populations arose solely by spontaneous mutations, then the most effective process for subsequently increasing the

prevalence of the beneficial mutations in the population over the course of generations is

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#Question id: 18797

#Unit 13. Methods in Biology

A replicating cells that have incorporated a high level of BrdU are exposed to light, they will

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#Question id: 11062

#Unit 7. System Physiology – Animal

The alveolar pressure of a normal 77-year-old woman is approximately 1 cm H2O during expiration. What is the alveolar pressure during inspiration (in cm H2O)?

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#Question id: 4335

#Unit 3. Fundamental Processes

Which of the following mutations would be most likely to have a harmful effect on an organism?