TLS Online TPP Program

#Question id: 2502


The important role that intermediate filaments play in the epithelial cells of the skin is evident in which of the following?

#Unit 2. Cellular Organization
  1. Individual keratin filaments span the cell membrane and directly connect one cell to the next.

  2. Knockout mice for a keratin gene like K14 exhibit stronger skin that can withstand abrasion.

  3. The polarity of keratin filaments allows them to withstand shear stress.

  4. Patients with mutations in keratin genes exhibit skin problems.