TLS Online TPP Program

#Question id: 2520


During the course of a muscle twitch (a contraction due to a single action potential), when is the free calcium concentration of the muscle cytoplasm highest?

#Unit 2. Cellular Organization
  1. milliseconds before the T tubule undergoes an action potential

  2. after the T tubule undergoes an action potential but before the muscle generates tension

  3. at the height of the tension generated by the muscle

  4. at the end of the twitch, after the muscle has relaxed

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TLS Online TPP Program

#Question id: 646

#Unit 1. Structure and Function of Biomolecules

Many biosynthetic pathways are regulated by feedback inhibition of enzymes. In a particular type of feedback inhibition, two endproducts individually do not inhibit an enzyme upstream in the pathway at all, but when both are present they inhibit the same enzyme significantly. What type of feedback inhibition do these inhibitors represent?

TLS Online TPP Program

#Question id: 647

#Unit 1. Structure and Function of Biomolecules

For the hypothetical reversible reaction where S is converted to P, the rate constant for the forward reaction is 105 s-1 while that of the backward reaction is 101 s-1. If the reaction is catalyzed by an enzyme, the rate constant for the forward reaction increases 100-fold. What will be the equilibrium constant of the enzyme catalyzed reaction?

TLS Online TPP Program

#Question id: 648

#Unit 1. Structure and Function of Biomolecules

Enzyme catalysis is regulated by a number of mechanisms. Also, the flux through metabolic pathways must be regulated. Given the metabolic pathway below, which choice accurately describes the regulation of compound G levels?

TLS Online TPP Program

#Question id: 649

#Unit 1. Structure and Function of Biomolecules

Choose INCORRECT statement from the following

TLS Online TPP Program

#Question id: 650

#Unit 1. Structure and Function of Biomolecules

On the basis of hypothetical binding curve given below, which of the following statement is INCORRECT

TLS Online TPP Program

#Question id: 651

#Unit 1. Structure and Function of Biomolecules

Consider an enzyme catalysed reaction treated with inhibitor. Enzyme kinetic was analysed with Eadie Hofstee equation. A plot of V0 versus V0/[S] for an enzyme-catalyzed reaction is shown below. The control curve was obtained in the absence of inhibitor. Which effect is shown on the enzyme activity when an inhibitor is added to the reaction mixture?