#Question id: 1521
#Unit 4. Cell Communication and Cell Signaling
we examine how the deregulation of growth-promoting and growth-inhibiting signaling pathways contributes to tumorigenesis. Mutations-
A. A mutation that alters a single amino acid (valine to glutamine) in the transmembrane region of the HER2 receptor
B. A deletion that causes loss of the extracellular ligand-binding domain in the EGF receptor Results-
i. dimerization of the receptor, even in the absence of the normal EGF-related ligand, transforming it into the oncoprotein, a constitutively active kinase
ii. to constitutive activation of the kinase activity of the resulting oncoprotein
iii. no dimerization, even in the presence of the normal EGF-related ligand, repression of kinase activity
which of the following results are displayed after these mutations?
#Question id: 19989
#Unit 2. Cellular Organization
#Question id: 28370
#Unit 5. Developmental Biology
the generation of dorsal/ventral axis in Drosophila, which protein signal causes follicle cells to differentiate into a dorsal axis of embryo?
#Question id: 7118
#Unit 5. Developmental Biology
At the molecular and cellular level, how does morphogenesis differ from establishment of embryonic axes and the specification of cellular identity?
#Question id: 19128
#Unit 12. Applied Biology