TLS Online TPP Program

#Question id: 2706


Which of the following is a function of a modified histone tail?

#Unit 2. Cellular Organization
  1. Association with adjacent nucleosome

  2. Interaction with DNA backbone

  3. Interaction with chromodomains

  4. Formation of 40-fold DNA structure

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TLS Online TPP Program

#Question id: 4396

#Unit 3. Fundamental Processes

It is suspected that a novel protein only interacts with the promoter region of a gene. Which of the following techniques should be used to confirm this suspicion?

A. EMSA

B. DNase footprinting

C. Filter binding

D. Gel mobility shift assay

TLS Online TPP Program

#Question id: 4397

#Unit 3. Fundamental Processes

Which of the following will prevent the activation of RNA polymerase, but not necessarily the assembly of eukaryotic general transcription factors at the promoter?

TLS Online TPP Program

#Question id: 4398

#Unit 3. Fundamental Processes

Which of the following are not found in DNA-binding proteins?

TLS Online TPP Program

#Question id: 4399

#Unit 3. Fundamental Processes

Transcription factors can

a. exhibit cooperative binding.  b. exist as heterodimers.

c. act to repress transcription of transcription factor genes.

d. undergo conformational changes which alter activity.

e. never interact with co-repressors.

TLS Online TPP Program

#Question id: 4400

#Unit 3. Fundamental Processes

Which is the first factor to bind at the promoter of eukaryotic genes?

a. RNA polymerase

b. TFIIA

c. TFIIB

d. TFIID 

e. TATA box–binding protein

TLS Online TPP Program

#Question id: 4401

#Unit 3. Fundamental Processes

Which of the following occur(s) during Pol II transcription preinitiation complex formation?

a. TFIIA binds to TFIIB.  b. TFIIB unwinds the DNA.

c. TFIIB contacts both TATA box–binding factor and DNA.

d. DNA bends.