TLS Online TPP Program

#Question id: 2724


When DNA is compacted by histones into 10 nm and 30 nm fibers, the DNA is unable to interact with proteins required for gene expression. Therefore, to allow for these proteins to act, the chromatin must constantly alter its structure. Which processes contribute to this dynamic activity?

#Unit 2. Cellular Organization
  1. DNA supercoiling at or around H1

  2. Methylation and phosphorylation of histone tails

  3. Hydrolysis of DNA molecules where they are wrapped around the nucleosome core

  4. Accessibility of heterochromatin to phosphorylating enzymes

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TLS Online TPP Program

#Question id: 459

#Unit 1. Molecules and their Interaction Relevant to Biology

Calculate △G°ʹ for the reaction shown if the mass action ratio, Q, is 5.3 × 102 M-1 and △G is 46 kJ/mol at a temperature of 298 K. (R = 8.315 J/K-mol)

ADP + Pi ⇌ ATP

TLS Online TPP Program

#Question id: 460

#Unit 1. Molecules and their Interaction Relevant to Biology

The hydrolysis of ATP to ADP has a △G°ʹ of -30 kJ/mol. If in an E. coli cell the concentrations of ATP, ADP and inorganic phosphate are 7.90 mM, 1.04 mM and 7.9 mM, respectively, which statement is true about the hydrolysis of ATP in the cell? (Assume a temperature of 298 K. R = 8.315 J/K-mol)

TLS Online TPP Program

#Question id: 461

#Unit 1. Molecules and their Interaction Relevant to Biology

The conversion of glucose-1-phosphate to glucose-6-phosphate by the enzyme phosphoglucomutase has a △G°ʹ of -7.6 kJ/mol. Calculate the equilibrium constant for this reaction at 298 K and a pH of 7. (R = 8.315 J/K-mol)

TLS Online TPP Program

#Question id: 462

#Unit 1. Molecules and their Interaction Relevant to Biology

The formation of acetyl CoA is driven to completion by

TLS Online TPP Program

#Question id: 463

#Unit 1. Molecules and their Interaction Relevant to Biology

Thioesters are similar to oxygen esters of carboxylic acids except that

TLS Online TPP Program

#Question id: 464

#Unit 1. Molecules and their Interaction Relevant to Biology

Calculate the equilibrium constant for an oxidation-reduction reaction involving the transfer of 1 mole of electrons with DE0ʹ= 0.25 V. (R = 8.315 JK-1mol-1, F = 96.48 kJV-1mol-1, T = 298 K)