TLS Online TPP Program

#Question id: 2851


There is a growing body of evidence that acetylation of histone N-termini in specific chromosomal regions contributes to gene control by regulating the binding of histones to DNA and regulation of the folding state of chromatin. The extent of histone acetylation is correlated with the relative resistance of chromatin DNA to digestion by nucleases. Which combination of histone acetylation state and DNAse 1 resistance is characteristic of actively transcribed regions of chromatin?

#Unit 2. Cellular Organization
  1. Little or no histone acetylation, highly resistant to DNAse 1

  2. Little or no histone acetylation, highly sensitive to DNAse 1

  3. High level of histone acetylation, highly resistant to DNAse 1

  4.  High level of histone acetylation, highly sensitive to DNAse 1