TLS Online TPP Program

#Question id: 2851


There is a growing body of evidence that acetylation of histone N-termini in specific chromosomal regions contributes to gene control by regulating the binding of histones to DNA and regulation of the folding state of chromatin. The extent of histone acetylation is correlated with the relative resistance of chromatin DNA to digestion by nucleases. Which combination of histone acetylation state and DNAse 1 resistance is characteristic of actively transcribed regions of chromatin?

#Unit 2. Cellular Organization
  1. Little or no histone acetylation, highly resistant to DNAse 1

  2. Little or no histone acetylation, highly sensitive to DNAse 1

  3. High level of histone acetylation, highly resistant to DNAse 1

  4.  High level of histone acetylation, highly sensitive to DNAse 1

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TLS Online TPP Program

#Question id: 69

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is the diastereomer of the following compound?

TLS Online TPP Program

#Question id: 70

#Unit 1. Molecules and their Interaction Relevant to Biology

The dimensions of living cells are limited, on the lower end by the minimum number of biomolecules necessary for function, and on the upper end by the rate of diffusion of solutes such as oxygen. Except for highly elongated cells, they usually have lengths and diameters in the range of

TLS Online TPP Program

#Question id: 71

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is not the priority rule for R, S Configuration?

TLS Online TPP Program

#Question id: 72

#Unit 1. Molecules and their Interaction Relevant to Biology

For the reaction catalyzed by the enzyme hexokinase: Glucose + ATP → glucose 6-phosphate + ADP the equilibrium constant, Keq, is 7.8 × 102. In living E. coli cells, [ATP] = 5 mM, [ADP] = 0.5 mM, [glucose] = 2 mM, and [glucose 6-phosphate] = 1 mM. Which of the following conclusions made on the basis of the above calculations is incorrect?

TLS Online TPP Program

#Question id: 73

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the Variation of Reaction Spontaneity (Sign of ΔG) given in Column I with the Signs of ΔH and ΔS given in column II.

COLUMN I

COLUMN II

 

 

 

  ΔH

ΔS

ΔG = ΔH – TΔS

1.

+

a. The reaction is both enthalpically and entropically opposed. It is nonspontaneous (endergonic) at all temperatures.

2.

 −

− 

b. The reaction is enthalpically opposed (endothermic) but entropically favored. It is spontaneous only at temperatures above T = ΔH/ΔS.

3.

+

+

c. The reaction is enthalpically favored but entropically opposed. It is spontaneous only at temperatures below T = ΔH/ΔS.

4.

+

d. The reaction is both enthalpically favored (exothermic) and entropically favored. It is spontaneous (exergonic) at all temperatures.

TLS Online TPP Program

#Question id: 73

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the Variation of Reaction Spontaneity (Sign of ΔG) given in Column I with the Signs of ΔH and ΔS given in column II.

COLUMN I

COLUMN II

 

 

 

  ΔH

ΔS

ΔG = ΔH – TΔS

1.

+

a. The reaction is both enthalpically and entropically opposed. It is nonspontaneous (endergonic) at all temperatures.

2.

 −

− 

b. The reaction is enthalpically opposed (endothermic) but entropically favored. It is spontaneous only at temperatures above T = ΔH/ΔS.

3.

+

+

c. The reaction is enthalpically favored but entropically opposed. It is spontaneous only at temperatures below T = ΔH/ΔS.

4.

+

d. The reaction is both enthalpically favored (exothermic) and entropically favored. It is spontaneous (exergonic) at all temperatures.