TLS Online TPP Program

#Question id: 2857


In one experiment, another protein –protein interaction is used in place of that between CAP and polymerase. This is done by taking two proteins known to interact with each other, attaching one to a DNA-binding domain, and, with the other, replacing the carboxy-terminal domain of the polymerase a subunit (aCTD), which one is appropriate result of this experiment-

I. The modified polymerase can be inhibited if the appropriate DNA-binding site is introduced near the promoter.

II. The modified polymerase can be activated by the makeshift “activator” as long as the appropriate DNA-binding site is introduced near the promoter.

III. The activator having only to help polymerase bind to the promoter

#Unit 2. Cellular Organization
  1. I & III True

  2. I & II False

  3. I & II False 

  4. Only III True

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TLS Online TPP Program

#Question id: 792

#Unit 1. Molecules and their Interaction Relevant to Biology

Which arm of the tRNA can act as a structural recognition feature?

TLS Online TPP Program

#Question id: 793

#Unit 1. Molecules and their Interaction Relevant to Biology

What is the average size (in bp) of a mature t-RNA?

TLS Online TPP Program

#Question id: 794

#Unit 1. Molecules and their Interaction Relevant to Biology

A single-stranded DNA molecule contains 40 nucleotides with equal amounts of A, C, G, and T. This DNA strand can combine with a complementary DNA strand to form a double-stranded DNA molecule. Which structural feature is found in the single-stranded DNA molecule?

TLS Online TPP Program

#Question id: 795

#Unit 1. Molecules and their Interaction Relevant to Biology

A single-stranded DNA molecule contains 40 nucleotides and has the sequence 5’-(GA)20-3’. When this single strand binds to a complementary DNA strand,

TLS Online TPP Program

#Question id: 796

#Unit 1. Molecules and their Interaction Relevant to Biology

Which statement best describes the distinction between the purposes of the two RNAi pathways within the eukaryotic cell?

TLS Online TPP Program

#Question id: 797

#Unit 1. Molecules and their Interaction Relevant to Biology

With respect to microRNAs, which, if any, of the following statements, is FALSE?)

A. MicroRNA genes often occur in gene clusters within introns of protein-coding genes and are usually transcribed by RNA polymerase II.

B. Like an mRNA a miRNA is initially produced as a larger precursor RNA that, like the great majority of mRNAs, usually has a 5’ cap and a poly(A) tail.

C. MicroRNAs are produced by germ-line cells only.

D. A miRNA is initially produced as a duplex RNA but in order to work it needs to be converted into a single-strand RNA.

E. MicroRNAs usually work as transcription factors.