TLS Online TPP Program

#Question id: 2871


With respect to X-chromosome inactivation in females, which, if any, of the following statements is incorrect?

#Unit 2. Cellular Organization
  1. X-inactivation first occurs in the preimplantation female mammalian embryo.

  2. One of the two X chromosomes in each diploid cell of a normal woman is randomly selected to undergo X-inactivation and becomes highly condensed.

  3. The process involves epigenetic silencing of each gene on one of the two X chromosomes, either the maternal X chromosome or the paternal X chromosome.

  4. Once the decision is made to inactivate a paternal X or the maternal X in a cell, all descendant cells will continue with that pattern of X-inactivation.

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TLS Online TPP Program

#Question id: 33395

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correct for Zinc Finger Motif 

a. Zinc atom stabilizes the structure / fold by coordination bonds. 
b. Each motif contains about 30-50 amino acids.
c. Contains regular patterns of Cys / His, which coordinate with Zinc atom.

TLS Online TPP Program

#Question id: 33396

#Unit 1. Molecules and their Interaction Relevant to Biology

In case of Coiled-coils 
a. Alpha-helices are packed together through the charged interactions only
b. They have heptad repeated sequences.
c. 3.6 aa / turn and 5.2A for a helix. 
d. abcdefg 'a' &'d’ are hydrophobic residues 'e' and 'g' are found to be charged amino.

Which of the following is correct

TLS Online TPP Program

#Question id: 33397

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following characterises domains

a. Highly conversed and may be common in most unrelated proteins.
b. They do not evolve.
c. Can function Independently.
d. Average 100 amino acids.
e. Single hydrophobic core.

TLS Online TPP Program

#Question id: 33398

#Unit 1. Molecules and their Interaction Relevant to Biology

Immunoglobulin fold is characterised by

TLS Online TPP Program

#Question id: 33399

#Unit 1. Molecules and their Interaction Relevant to Biology

Transmembrane β barrels of known structure consist of 

TLS Online TPP Program

#Question id: 33400

#Unit 1. Molecules and their Interaction Relevant to Biology

Green fluorescent protein is