TLS Online TPP Program

#Question id: 2883


Which, if any, of the following statements is incorrect?

I. In X-chromosome inactivation, the inactivated X chromosome is epigenetically silenced by a transcript, the XIST RNA, that is produced from the active X chromosome.

II. The XIST RNA works by coating most of the X chromosome that is to be inactivated and then recruiting Polycomb proteins to condense the chromosome.

III. The inactivated X chromosome carries the kinds of histone modification that are typical of heterochromatin.

IV. The pattern of X-chromosome inactivation is made randomly but once it has been established the same pattern of X-inactivation is propagated through all mitotic and meiotic cell divisions.

#Unit 2. Cellular Organization
  1. I and III only

  2. I and IV only

  3. I, II and III only

  4. II and IV only