Which, if any, of the following statements is incorrect?

I. In X-chromosome inactivation, the inactivated X chromosome is epigenetically silenced by a transcript, the XIST RNA, that is produced from the active X chromosome.

II. The XIST RNA works by coating most of the X chromosome that is to be inactivated and then recruiting Polycomb proteins to condense the chromosome.

III. The inactivated X chromosome carries the kinds of histone modification that are typical of heterochromatin.

IV. The pattern of X-chromosome inactivation is made randomly but once it has been established the same pattern of X-inactivation is propagated through all mitotic and meiotic cell divisions.

#Question id: 5360

#Unit 1. Molecules and their Interaction Relevant to Biology

Following some different genetic disorder traces in families. 

 Which of the following possible mode of inheritance in the Family A, B, C and D respectively

#Question id: 5360

#Unit 8. Inheritance Biology

Following some different genetic disorder traces in families. 

 Which of the following possible mode of inheritance in the Family A, B, C and D respectively

#Question id: 5361

#Unit 8. Inheritance Biology

The pedigree shows the inheritance of a RFLP marker through three generations in a single family. A total of 8 alleles (numbered to the left of the blots) are present in the family. The RFLPs of each member of the family are placed directly below his (squares) or her (circles) symbol and RFLP numbers. In Above pedigree, which of the following are not children of second generation parent?

#Question id: 5362

#Unit 8. Inheritance Biology

From the following select the possible mode of inheritance and the probability that the daughter in generation III will show the trait.

#Question id: 5363

#Unit 8. Inheritance Biology

A Southern blot using a probe that binds to the region spanning the mutation causing albinism detects one DNA fragment in homozygous normal individuals (A/A) and two fragments in albino individuals (a/a). Following banding pattern of three offspring of parents? Which of the following correct regarding parents?

#Question id: 5364

#Unit 8. Inheritance Biology

The inheritance of a given disorder is recorded in families shown below: Based on the above limited information, which one of the following inheritance patterns of disorder was not shown in the family?