TLS Online TPP Program

#Question id: 2892


The edges of each base pair are exposed in the major and minor grooves, creating a pattern of hydrogen-bond donors and acceptors and of hydrophobic groups (allowing for Vander Waals interactions) that identifies the base pair. The edge of an T : A base pair displays the following chemical groups in the following order in the major groove:

#Unit 2. Cellular Organization
  1. A hydrogen-bond acceptor (N7 of adenine), a hydrogen-bond donor (C6 of adenine), a hydrogen-bond acceptor (C4 of thymine), and a bulky hydrophobic surface (the methyl group on C5 of thymine).

  2. A hydrogen-bond donor (N7 of adenine), a hydrogen-bond acceptor (C6 of adenine), a hydrogen-bond acceptor (C4 of thymine), and a bulky hydrophobic surface (the methyl group on C5 of thymine).

  3. A hydrogen-bond acceptor (N7 of adenine), a hydrogen-bond donor (C6 of adenine), a hydrogen-bond donor (C4 of thymine), and a bulky hydrophobic surface (the methyl group on C5 of thymine).

  4. A bulky hydrophobic surface (the methyl group on C5 of thymine), a hydrogen-bond acceptor (C4 of thymine), a hydrogen-bond donor (C6 of adenine), A hydrogen-bond acceptor (N7 of adenine).