TLS Online TPP Program

#Question id: 2894


Which of the following statements is INCORRECT regarding the assembly of DNA into higher-order chromatin structure?

I. Histone H1 is not part of the histone octamer, but binds to linker DNA and is responsible for higher-order chromatin structure.

II. The 30 nm fibers of a chromosome are attached to a/an RNA-protein scaffold that holds the fibers in large loops.

III. It is not possible for linear DNA to be supercoiled. Only circular DNA, which has no ends, can have regions of supercoiling.

IV. Core histones lacking their amino-terminal tails are capable of forming 30-nm fibers as they help to stabilize the 30-nm fiber in internucleosomal interactions.

#Unit 2. Cellular Organization
  1. II only

  2. I and II only

  3. III only

  4. III and IV only