Following statements are regarding to control of the G1–S phase transition in budding yeast.

A. G1 cyclin-CDK complexes stimulate the formation of G1/S phase cyclin-CDKs, which then initiate bud formation, centrosome duplication, and DNA replication. In yeast, the G1 cyclin gene is called CLN3.

B. Once sufficient Cln3 is synthesized from its mRNA, Cln3-CDK complexes phosphorylate and activate the transcriptional repressor Whi5.

C. Phosphorylation of Whi5 promotes its export out of the nucleus, allowing the transcription factor complex SBF to induce transcription of the G1/S phase cyclin genes CLN1 and CLN2 as well as other genes important for DNA replication.

D. Once produced, Cln1/2-CDKs contribute to further Whi5 phosphorylation. This positive feedback loop ensures the rapid accumulation of G1/S phase cyclin-CDKs.

Which of the following statements are correct?

#Question id: 2847

#Unit 2. Cellular Organization

Select the answer that describes a region of DNA in which genes are likely to be located.

#Question id: 2848

#Unit 2. Cellular Organization

Select the answer that names the three functional elements that are required for replication and stable inheritance of chromosomes

#Question id: 2849

#Unit 2. Cellular Organization

Methylation of lysines 4, 36, or 79 of histone H3 typically is associated……… of the genes, whereas methylation of lysines 9 or 27 of the same histone frequently is associated with …..

#Question id: 2850

#Unit 2. Cellular Organization

CCA-adding enzymes add a specific sequence without a template because

#Question id: 2851

#Unit 2. Cellular Organization

There is a growing body of evidence that acetylation of histone N-termini in specific chromosomal regions contributes to gene control by regulating the binding of histones to DNA and regulation of the folding state of chromatin. The extent of histone acetylation is correlated with the relative resistance of chromatin DNA to digestion by nucleases. Which combination of histone acetylation state and DNAse 1 resistance is characteristic of actively transcribed regions of chromatin?

#Question id: 2852

#Unit 2. Cellular Organization

The chromosomal karyotypes of two species of small deer, the Reeves muntjac and the Indian muntjac, are strikingly different despite the fact that the two genomes contain about the same amount of DNA. However, within a species, there are properties of chromosomes that are the same, i.e. species-specific. Select the answer that contains all of these species-specific properties of chromosomes at metaphase