Mitotic CDK complexes are maintained in an inactive state through inhibitory phosphorylation of the CDK subunit. Two highly conserved tyrosine and threonine residues in mammalian CDKs are subject to regulated phosphorylation.

Gene	Mutant phenotypes
A. Wee1	i. the cell does not divide but continues to grow
B. CAK kinase	ii. mitotic cyclins are inactivated
C. cdc25 phosphatase	iii. premature entry into mitosis

The following table enlists genes and phenotypes observed on mutation of these genes but not correctly matched. Which one of the following combinations is correctly matched ?

TLS Online TPP Program

#Question id: 19709

#Unit 3. Fundamental Processes

Following are statements related to the telomere related to the stability chromosome

a) protecting the ends of chromosomes from degradation 

b) preventing chromosomal end fusion

c) protect genome from nucleolytic degradation

d) provide a mechanism for their replication by semiconservative length maintenance 

choose the correct statement 

TLS Online TPP Program

#Question id: 19710

#Unit 3. Fundamental Processes

Telomeric sequences can be written in the general form 

TLS Online TPP Program

#Question id: 19711

#Unit 3. Fundamental Processes

Telomere are marker for the healthy cell, if the cell shows indefinite replication (embryonic or stem cell) the size of telomere lies between the range of  

TLS Online TPP Program

#Question id: 19712

#Unit 3. Fundamental Processes

Size of telomeric sequences are marker for the cell division and healthy cell,  Below some of the stages and sizes of telomere are given below

i. 3 – 20 kb (TTAGGG)n	a. cancerous cell
ii. less than 3 kb (TTAGGG)n	b. apoptotic cell death
iii. Ends with no (TTAGGG)n	c. limited replication
iv. Up to 55 kb of (TTAGGG)n	d. indefinite replication

Match them correctly

TLS Online TPP Program

#Question id: 19713

#Unit 3. Fundamental Processes

Which of the followings is the incorrect statement regarding telomeric sequences 

TLS Online TPP Program

#Question id: 19714

#Unit 3. Fundamental Processes

The extension of GGGGTT is prioritize, while the extension of CCCCAA is not possible because of