#Question id: 53
#Unit 1. Molecules and their Interaction Relevant to Biology
Calculate the number of times the DNA of a modern E. coli cell has been copied accurately since its earliest bacterial precursor cell arose about 3.5 billion years ago. Assume for simplicity that over this time period, E. coli has undergone, on average, one cell division every 12 hours (this is an overestimate for modern bacteria, but probably an underestimate for ancient bacteria).
#Question id: 19813
#Unit 12. Applied Biology
#Question id: 28567
#Unit 5. Developmental Biology
How the cAMP phosphodiesterase RegA plays a crucial role in regulating intracellular cAMP levels cells & level of PKA activity?
#Question id: 2508
#Unit 2. Cellular Organization
If you treated cells with a drug that interferes with microtubules, such as colchicine, which of the following would result?
A. Cell shape would be disrupted.
B. Mitosis and meiosis would not occur.
C. The intracellular location of organelles would be disrupted.
#Question id: 2973
#Unit 2. Cellular Organization
Following statements are regarding to the spindle position checkpoint pathway in budding yeast.
A. During interphase and early mitosis, Cdc14 is sequestered and inactivated in the nucleolus. Inactive Tem1-GDP associates with the spindle pole body (SPB) nearest to the bud as soon as the mitotic spindle forms.
B. If chromosome segregation occurs properly, extension of the spindle microtubules inserts the daughter SPB into the bud, causing Tem1 to be activated by an unknown mechanism.
C. Tem1-GDP activates a protein kinase cascade, which then promotes the release of active Cdc14 from the nucleolus and exit from mitosis.
D. If the spindle apparatus fails to place the daughter SPB in the bud, Kin4 (cyan), an inhibitor of Tem1, is recruited from the parent cell cortex to the parent-cell-located SPB and maintains Tem1 in the GTP-bound form, and mitotic exit does not occur.
Which of the following are correct?