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TLS Online TPP Program

#Question id: 24281

Which of the following statement describes inside-out signaling?

#Unit 4. Cell Communication and Cell Signaling
  1. Binding of integrins to their ligands induces conformational changes in their cytoplasmic domains, directly or indirectly altering their interactions with cytoplasmic proteins
  2. Binding of integrins to their ligands induces conformational changes in their transmembrane domains, directly or indirectly altering their interactions with cytoplasmic proteins
  3. Binding of cytoskeletal proteins intracellularly induces conformational changes in extracellular domains of integrins, so it unable to bind to the ligands
  4. intracellular signaling pathways can, via adapter proteins, modify the ability of integrins to bind to their extracellular ligands
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TLS Online TPP Program

#Question id: 28395

#Unit 5. Developmental Biology

One of the genes activated by VegT protein encodes the Sox17 transcription factor , these sox17 transcription factor is critical for which functions?
TLS Online TPP Program

#Question id: 28396

#Unit 5. Developmental Biology

VegT is critical in generating the germ cells, two genes activated by VegT protein that encodes the transcriptional factor as well as paracrine factors that instruct the cell layers to become their fate. which of the following statements is incorrect?
a) Sox17 paracrine factor that specify cells to be endoderm
b) Nodal transcription factors that instruct the cell layers above them to become mesoderm
c) Nodal paracrine factors that instruct the cell layers above them to become mesoderm
d) Sox17 transcription factor that specify cells to be endoderm
TLS Online TPP Program

#Question id: 28397

#Unit 5. Developmental Biology

During the specification of amphibian axes, in the absence of any induction cell leads to become which of the following fate?
TLS Online TPP Program

#Question id: 28398

#Unit 5. Developmental Biology

Spemann referred to the dorsal lip cells and their derivatives as the organizer, these derivatives cells are___
TLS Online TPP Program

#Question id: 28399

#Unit 5. Developmental Biology

Dorsal most vegetal cells of the blastula, which are capable of inducing the organizer is known as____
TLS Online TPP Program

#Question id: 28400

#Unit 5. Developmental Biology

Which of the following is the major candidate for the factor that forms the Nieuwkoop center ?