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TLS Online TPP Program

#Question id: 24282

Which of the following statement describes outside-in signaling?

#Unit 4. Cell Communication and Cell Signaling
  1. Binding of integrins to their ligands induces conformational changes in their cytoplasmic domains, directly or indirectly altering their interactions with cytoplasmic proteins
  2. Binding of integrins to their ligands induces conformational changes in their transmembrane domains, directly or indirectly altering their interactions with cytoplasmic proteins
  3. Binding of cytoskeletal proteins intracellularly induces conformational changes in extracellular domains of integrins, so it unable to bind to the ligands
  4. intracellular signaling pathways can, via adapter proteins, modify the ability of integrins to bind to their extracellular ligands
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TLS Online TPP Program

#Question id: 2821

#Unit 2. Cellular Organization

Which of the following is (are) encoded by multiple genes present in the human genome?

a. ribosomal RNA       b. transfer RNA                       c. histone            d. lysozyme
TLS Online TPP Program

#Question id: 2822

#Unit 2. Cellular Organization

Transposition by a bacterial insertion element

a. occurs at a frequency of approximately 1 in 10^3 cells per generation.

b. can inactivate an essential gene.    

c. is mediated through a RNA intermediate.

d. requires the enzyme transposase
TLS Online TPP Program

#Question id: 2823

#Unit 2. Cellular Organization

Transposition by a retrotransposon requires activity of which of the following enzymes?

a. RNA polymerase                b. reverse transcriptase

c. DNA methylase                  d. DNA polymerase
TLS Online TPP Program

#Question id: 2824

#Unit 2. Cellular Organization

Plant mitochondrial DNA

a. is the same size as human mitochondrial DNA.

b. encodes a 5S mitochondrial rRNA.

c. contains multiple copies that recombine with each other.

d. uses the standard genetic code.
TLS Online TPP Program

#Question id: 2825

#Unit 2. Cellular Organization

Metaphase chromosomes can be identified

a. by shape.                 

b. by the size and number of introns.

c. by banding patterns with Giemsa reagent.

d. by chromosome painting.
TLS Online TPP Program

#Question id: 2826

#Unit 2. Cellular Organization

An open reading frame (ORF) is defined as a DNA sequence that

a. begins with a start codon.               

b. ends with a stop codon.

c. contains 50 codons.   

d. contains approximately an equal frequency of A, T, G, and C.