AZT (3'-azido-2',3'-dideoxythymidine), used to treat HIV infection, acts in HIV-infected cells by:

#Question id: 646

#Unit 1. Structure and Function of Biomolecules

Many biosynthetic pathways are regulated by feedback inhibition of enzymes. In a particular type of feedback inhibition, two endproducts individually do not inhibit an enzyme upstream in the pathway at all, but when both are present they inhibit the same enzyme significantly. What type of feedback inhibition do these inhibitors represent?

#Question id: 647

#Unit 1. Structure and Function of Biomolecules

For the hypothetical reversible reaction where S is converted to P, the rate constant for the forward reaction is 10⁵ s^-1 while that of the backward reaction is 10¹ s_-1. If the reaction is catalyzed by an enzyme, the rate constant for the forward reaction increases 100-fold. What will be the equilibrium constant of the enzyme catalyzed reaction?

#Question id: 648

#Unit 1. Structure and Function of Biomolecules

Enzyme catalysis is regulated by a number of mechanisms. Also, the flux through metabolic pathways must be regulated. Given the metabolic pathway below, which choice accurately describes the regulation of compound G levels?

#Question id: 649

#Unit 1. Structure and Function of Biomolecules

Choose INCORRECT statement from the following

#Question id: 650

#Unit 1. Structure and Function of Biomolecules

On the basis of hypothetical binding curve given below, which of the following statement is INCORRECT

#Question id: 651

#Unit 1. Structure and Function of Biomolecules

Consider an enzyme catalysed reaction treated with inhibitor. Enzyme kinetic was analysed with Eadie Hofstee equation. A plot of V0 versus V0/[S] for an enzyme-catalyzed reaction is shown below. The control curve was obtained in the absence of inhibitor. Which effect is shown on the enzyme activity when an inhibitor is added to the reaction mixture?