There are three type of Splicing signals 1. Major U2-type or GU-AG introns 2. Minor U12-type or AU-AC introns & 3. Minor U12-type with GU-AG introns (hybrid type), which of the following is responsible for the recognition of branch point sequence UACUAAC?

#Question id: 3806

#Unit 3. Fundamental Processes

How are damaged nucleotides recognized by DNA repair enzymes?

#Question id: 3807

#Unit 3. Fundamental Processes

If the genes from the following list were damaged, which gene would most likely be repaired first?

#Question id: 3808

#Unit 3. Fundamental Processes

Fibroblast cells from several different xeroderma pigmentosa patients were cultured, then fused in intergenic complementation studies. Which cell fusions would not result in a hybrid capable of repairing damaged DNA?

#Question id: 3809

#Unit 3. Fundamental Processes

MMR is a highly conserved biological pathway. Several human MMR proteins have been identified based on their homology to E. coli MMR proteins. Match the following

#Question id: 3810

#Unit 3. Fundamental Processes

In the diagram below, the dotted line marks the point of initiation of bidirectional replication

A. On the right side of the dotted line, leading strand synthesis occurs using the lower strand as the template.

B. On the right side of the dotted line, leading strand synthesis occurs using the upper strand as the template.

C. A ligase deficient (lig- ) mutant would affect replication of t11e upper strand on the left side of the dotted line.

D. A ligase deficient (lig- ) mutant would affect replication of the lower strand on the left side

of the dotted line_

Which one of the following options represents the combinations of the CORRECT statements?

#Question id: 3811

#Unit 3. Fundamental Processes

The mechanism of DNA replication is studied in an E. coli replication fork. Which is a characteristic of this replication fork?