There are three type of Splicing signals 1. Major U2-type or GU-AG introns 2. Minor U12-type or AU-AC introns & 3. Minor U12-type with GU-AG introns (hybrid type), which of the following is responsible for the recognition of branch point sequence CCUUAACU

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#Question id: 14763

#Unit 2. Cellular Organization

Which of the following graph shows G-actin polymerize into F-actin.

 

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#Question id: 14764

#Unit 2. Cellular Organization

Match the following proteins (Column I) with their function (Column II). Which of the following is correct?

Column I	Column II
a. Profilin	i. binds to the (+) end of an actin filament, thereby inhibiting subunit addition or loss.
b. Cofilin	ii. blocks (−) ends, inhibits filament disassembly, to stabilize filaments
c. Thymosin-β4	iii. involved in actin treadmilling, but it binds specifically to F-actin in which the subunits contain ADP
d. Cap Z	iv. binds ADP–G-actin and catalyzes the exchange of ADP for ATP
e. Tropomodulin	v. binds to ATP–G-actin in such a way that it inhibits addition of the actin subunit to either end of the filament.

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#Question id: 14765

#Unit 2. Cellular Organization

Following statements are regarding to the formins which involve in filament assembly.

A. All formin family members have two adjacent domains in common, the so called FH1 and FH2 domains (formin-homology domains 1 and 2).

B. Two FH2 domains from two individual formin monomers associate to form a doughnut-shaped complex can form a dimer and nucleate filament assembly.

C. The FH1 domain of formin is rich in proline residues, which serve as sites for the binding of several profilin molecules.

D. The FH2 domain behaves as a landing site for profilin–ATP–G-actin to increase the local concentration of these complexes.

E. Formins are activated by membrane bound Rho-GTP, a Ras-related small GTPase.

Which of the following combination is correct?

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#Question id: 14766

#Unit 2. Cellular Organization

Which of the following statements does not belongs to the regulatory mechanism of the Arp2/3 complex by WASp and PI(4,5)P2?

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#Question id: 14771

#Unit 13. Methods in Biology

What is the chance of throwing a number greater than 4 with an ordinary die whose faces are numbered from 1 to 6 ?

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#Question id: 14772

#Unit 13. Methods in Biology

Find the chance of throwing at least one ace in a simple throw with two dice numbered 1 to 6.