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TLS Online TPP Program

#Question id: 24553

113 Sequence divergence of genome are carried out by accumulating mutagens with time, according to the given graph which of the following prediction are correct about the codon position of the genome?

#Unit 9. Diversity of Life Forms
  1. A-third no of codon highly evolved , B-second no of codon mutation lowest with the third codon, C-first no of  codon most slowly evolve
  2. A-first no of codon highly evolved , B-second no of codon mutation highest with the third codon, C- third no of  codon most slowly evolve
  3. A-second no of codon highly evolved , B-first no of codon mutation highest with the third codon , C-third no of  codon most slowly evolve
  4. A-third no of codon highly evolved, B-first no of codon mutation highest with the second codon, C-second no of  codon most slowly evolve
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TLS Online TPP Program

#Question id: 1227

#Unit 4. Cell Communication and Cell Signaling

Which of the following is a mechanism for down regulation of signaling from G protein-coupled receptors?

a. a change in the Kd of the receptor-hormone complex

b. proteolysis of the Gα subunit                     

c. hydrolysis of cAMP to 5´-AMP

d. dephosphorylation of adenylyl cyclase
TLS Online TPP Program

#Question id: 1228

#Unit 4. Cell Communication and Cell Signaling

Place the events that follow the binding of a ligand to a G protein-coupled receptor that acts on adenylyl cyclase in the correct order:

a. GTP is hydrolyzed to GDP.           

b. GDP is displaced from Gα.           

c. the Gα-GTP complex dissociates from the Gβγcomplex.  

d. GTP is bound to Gα. 
TLS Online TPP Program

#Question id: 1229

#Unit 4. Cell Communication and Cell Signaling

Which of the following events occur(s) during light activation of the rhodopsin receptor?

a. 11-cis-retinal is converted to all-trans-retinal

b. activation of the trimeric G protein, transducin

c. activation of cGMP phosphodiesterase

d. opening of the cGMP-gated ion channel
TLS Online TPP Program

#Question id: 1230

#Unit 4. Cell Communication and Cell Signaling

Which of the following events occur(s) following the binding of a ligand to a G protein–coupled receptor that triggers release of Ca2+?

a. activation of protein kinase A by IP3

b. phospholipase cleavage of PIP2 to IP3 and DAG

c. release of DAG into the cytosol

d. IP3-mediated opening of Ca2+ channels in the ER membrane
TLS Online TPP Program

#Question id: 1231

#Unit 4. Cell Communication and Cell Signaling

Arrange the following events in the proper order in which they occur during transduction of the TGFβ signal:

a. association of Smad3 and Smad4  

b. phosphorylation of TGFβ receptor I by TGFβ receptor II            

c. phosphorylation of Smad3 by TGFβ receptor I     

d. nuclear import of Smad3   

e. binding of TGFβ to TGFβ receptor II  
TLS Online TPP Program

#Question id: 1232

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following mutations might confer a competitive advantage to an athlete by raising his or her hematocrit?

a. excess production of erythropoietin                       

b. decreased production of erythropoietin

c. EpoR that cannot bind STAT5                  

d. EpoR that cannot bind SHP1

e. EpoR that cannot bind JAK2