#Question id: 2810
#Unit 2. Cellular Organization
Which of the following steps is required to generate a knockout mouse?
a. microinjection of DNA into the pronucleus of a fertilized mouse egg
b. introduction of DNA into mouse embryonic stem cells
c. selection for cells containing the gene targeted insertion
d. expression of Cre protein during embryonic development
#Question id: 2811
#Unit 2. Cellular Organization
RNA interference is a method for inhibiting the function of specific genes using
a. single-stranded DNA.
b. double-stranded DNA.
c. single-stranded RNA.
d. double-stranded RNA.
#Question id: 2812
#Unit 2. Cellular Organization
Which of the following statements is (are) true of the human genome?
a. 1.5 percent of the genome corresponds to protein coding sequences.
b. The median length of an intron is 10 kb.
c. 10 percent of the genome is transcribed into pre mRNA precursors.
d. Most human exons contain 500–1000 base pairs.
#Question id: 2813
#Unit 2. Cellular Organization
DNA fingerprinting is a technique based on differences in the
a. length of introns.
b. number of tandem copies of a simple sequence repeat.
c. number of tandem ribosomal RNA genes.
d. size of protein coding genes.
#Question id: 2814
#Unit 2. Cellular Organization
LINES (long interspersed elements)
#Question id: 2815
#Unit 2. Cellular Organization
Telomerase
a. extends DNA strands during DNA synthesis.
b. has reverse transcriptase activity.
c. is a protein-RNA complex.
d. replicates repetitious DNA located at the centromere.