TLS Online TPP Program

#Question id: 4101


In order to ensure that only fully processed mature mRNAs are allowed to be exported to cytosol, pre-mRNAs associated with snRNPs are retained in the nucleus. To demonstrate this, an experiment was performed where a gene coding a pre-mRNA with a single intron was mutated either at the 5’ or 3’ splice sites or both the splice sites.

Given below are a few possible outcomes, Choose NOT FEASIBLE OUTCOME

A. Pre-mRNA having mutation at both the splice sites will be retained in the nucleus because of the presence of bound snRNPs.

B. Pre-mRNA having mutation at both the splice sites will be exported to cytosol because of the absence of bound snRNPs.

C. Pre-mRNA mutated at either 3’ or 5’ splice sites will be retained in the nucleus because of the presence of bound snRNPs.

D. Pre-mRNA mutated at either 3’ or 5’ splice sites will be exported to cytosol because of the absence of bound snRNPs.

#Unit 3. Fundamental Processes
  1. B and C   

  2. A and D

  3. B and D   

  4. A and C

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TLS Online TPP Program

#Question id: 5755

#Unit 8. Inheritance Biology

A researcher studying bacterial toxin predicts that a lysine within the toxin is important for binding it’s target cell.  She used site-directed mutagenesis to change a codon for lysine (AAA) to one for asparagine (AAU).  However, the mutant toxin still binds to its target cell just as well as the wild-type toxin bound and appears to have no other changes. This type of mutation is probably

TLS Online TPP Program

#Question id: 5756

#Unit 8. Inheritance Biology

Type of mutation caused by an addition or deletion of a base in a polypeptide-encoding part of a gene

TLS Online TPP Program

#Question id: 5757

#Unit 8. Inheritance Biology

A new E. coli mutant was tested for auxotrophy. The mutant grows on:

minimal medium (M) + arginine (A) + proline (P)

M + P + histidine (H)

M + A + H + P

but not on M or on M + A + H. The mutant requires

TLS Online TPP Program

#Question id: 5758

#Unit 8. Inheritance Biology

Consider a species with a diploid (2n) number of 28 chromosomes. How many chromosomes would be found in a monoploid body cell?

TLS Online TPP Program

#Question id: 5760

#Unit 8. Inheritance Biology

The fluctuation test of Luria and Delbruck (studying resistance to bacteriophge T1 infection) established that

TLS Online TPP Program

#Question id: 5761

#Unit 8. Inheritance Biology

E. coli cells were spread on an agar plate, producing 1000 colonies.  The colonies are replica plated on two agar plates containing the antibiotic kanamycin and one agar plate without antibiotics.  All of the colonies are able to grow on the agar plate without antibiotic but only 4 colonies are able to grow on each of the agar plates containing kanamycin.  You notice that the four colonies that grew on each of the kanamycin containing plates are in the exact same position.  This demonstrates