Imagine that you have created a fusion between the Trp operon, which encodes the enzymes for tryptophan biosynthesis, and the Lac operon, which encodes the enzymes necessary for lactose utilization. Under which set of conditions (A–F below) will β-galactosidase be expressed in the strain that carries the fused operon?

A. Only when lactose and glucose are both absent.

B. Only when lactose and glucose are both present.

C. Only when lactose is absent and glucose is present.

D. Only when lactose is present and glucose is absent.

E. Only when tryptophan is absent.

F. Only when tryptophan is present.

TLS Online TPP Program

#Question id: 19116

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                             

Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR42 in Family 2.

TLS Online TPP Program

#Question id: 19117

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

 

Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR43 in Family 2.

TLS Online TPP Program

#Question id: 19118

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                               

Calculate LOD scores for linkage at θ= 0.02 between SSR42 and SSR43 in Family 1.

TLS Online TPP Program

#Question id: 19119

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                     

Calculate LOD scores for linkage at θ= 0.02 between SSR42 and SSR43 in Family 2.

TLS Online TPP Program

#Question id: 19120

#Unit 8. Inheritance Biology

Trisomy 18 is one of the most common trisomies observed in human populations. You prepare DNA samples from two unrelated infants, both with trisomy 18, and from their parents. You then type the infants and their parents for four SSRs distributed along chromosome 18:

 

                                      

In which parent did nondisjunction occur in Family 1?

TLS Online TPP Program

#Question id: 19121

#Unit 8. Inheritance Biology

Trisomy 18 is one of the most common trisomies observed in human populations. You prepare DNA samples from two unrelated infants, both with trisomy 18, and from their parents. You then type the infants and their parents for four SSRs distributed along chromosome 18:

 

                                              

In which parent did nondisjunction occur in Family 2?