#Question id: 4354
#Unit 3. Fundamental Processes
Which of the following statements correctly describes the primary difference between enhancers and proximal control elements?
#Question id: 28804
#Unit 2. Cellular Organization
#Question id: 4050
#Unit 3. Fundamental Processes
An antibody was produced and used in an immunohistochemical assay to detect the location of RNA polymerase II in a thin section of a liver biopsy. The section was stained with the antibody that had been labeled with a fluorescent tag, and then viewed under a fluorescent microscope. State where you would expect to find positive staining if the enzyme is present.
#Question id: 889
#Unit 1. Molecules and their Interaction Relevant to Biology
The cis and trans GroEL rings undergo conformational changes in a reciprocating fashion, with events in one ring influencing events in the other ring. The entire GroEL/ES chaperonin complex functions as follows;
a) One GroEL ring that has bound 7 ATP also binds an improperly folded substrate protein, which associates with hydrophobic patches that line the inner wall of the GroEL chamber
b) The GroES cap then binds to the GroEL ring like a lid on a pot, inducing a conformational change in the resulting cis ring
c) Within ~10 s the cis ring catalyzes the hydrolysis of its 7 bound ATPs and releases the resulting Pi , which weakens the interactions binding GroES to GroEL
d) A second molecule of improperly folded substrate protein binds to the cis ring, followed by 7 ATP
e) The binding of substrate protein and ATP to the cis ring conformationally induces the trans ring to release its bound GroES, 7 ADP, and the presumably now better-folded substrate protein
Which of the following is incorrect functions of GroEL/ES chaperonin complex?
#Question id: 28735
#Unit 2. Cellular Organization