Arrange the events listed below in order according to the signal hypothesis:

I. Signal sequence binds to SRP

II. Translation stops

III. Translation starts

IV. Ribophorins anchor complex

V. SRP dissociates; GTP hydrolyzed

VI. SRP-signal complex binds to docking protein

#Question id: 1132

#Unit 4. Cell Communication and Cell Signaling

Which of the following become(s) active as a kinase when an activation lip residue is phosphorylated?

a. EpoR                       b. JAK             c. STAT           d. Ras              e. MAPK

#Question id: 1133

#Unit 4. Cell Communication and Cell Signaling

What tertiary structure characterizes all cytokines?

#Question id: 1134

#Unit 4. Cell Communication and Cell Signaling

Arrange the following proteins in the proper order in which they become activated in the MAPK signaling pathway:

a. MAP kinase                         b. MEK           c. Ras              d. Raf              e. RTK            

#Question id: 1135

#Unit 4. Cell Communication and Cell Signaling

Which of the following is a direct substrate of MAP kinase?

a. TCF             b. SRF             c. SRE             d. p90RSK      e. CREB

#Question id: 1136

#Unit 4. Cell Communication and Cell Signaling

Which of the following signaling pathways can be activated by activation of receptor tyrosine kinases?

a. phospholipase Cγ                b. PI-3 kinase

c. MAP kinase                         d. none of the above

#Question id: 1137

#Unit 4. Cell Communication and Cell Signaling

A loss-of-function mutation in PTEN phosphatase results in

a. increased cell proliferation.            

b. decreased cell proliferation.

c. increased apoptosis.                                   

d. decreased apoptosis.