Once researchers identified DNA as the molecule responsible for transmitting heritable traits, they asked how information was transferred from the DNA in the nucleus to the site of protein synthesis in the cytoplasm. Which of the following statements correctly describes the mechanism of information transfer in eukaryotes that accomplishes this task?

#Question id: 14502

#Unit 13. Methods in Biology

#Question id: 19098

#Unit 4. Cell Communication and Cell Signaling

#Question id: 1621

#Unit 4. Cell Communication and Cell Signaling

Eosinophils do NOT:

#Question id: 4104

#Unit 3. Fundamental Processes

Consider following statements for catalytic mechanism of RNA polymerase

A. RNA synthesis by RNA polymerase. The reaction involves two Mg2+ ions, coordinated to the phosphate groups of the incoming nucleoside triphosphates (NTPs)

B. Three Asp residues, which are highly conserved in the RNA polymerases of all species. One Mg2+ ion facilitates attack by the 39-hydroxyl group on the phosphate of the NTP; the other Mg2+ ion facilitates displacement of the pyrophosphate, and both metal ions stabilize the pentacovalent transition state.

C. About 17 bp of DNA are unwound at any given time. RNA polymerase and the transcription bubble move from left to right along the DNA as shown, facilitating RNA synthesis. Movement of an RNA polymerase along DNA tends to create negative supercoils (overwound DNA) ahead of the transcription bubble and positive supercoils (underwound DNA) behind it.

D. The RNA polymerase is in close contact with the DNA ahead of the transcription bubble as well as with the separated DNA strands and the RNA within and immediately behind the bubble. A channel in the protein funnels new NTPs to the polymerase active site. The polymerase footprint encompasses about 35 bp of DNA during elongation.

#Question id: 4229

#Unit 3. Fundamental Processes

Which of the following processes occurs during transcription?