TLS Online TPP Program

#Question id: 4253


The most commonly occurring mutation in people with cystic fibrosis is a deletion of a single codon. What is the result of this type of mutation?

#Unit 3. Fundamental Processes
  1. a base-pair substitution

  2. a frameshift mutation

  3. a polypeptide missing an amino acid

  4. a nonsense mutation

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TLS Online TPP Program

#Question id: 740

#Unit 1. Molecules and their Interaction Relevant to Biology

The conformation of the backbone of a polypeptide is described completely by the angle(s) of rotation about which bond(s)?

TLS Online TPP Program

#Question id: 741

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of following statements are INCORRECT about secondary structure of proteins

A. Long block of Glu residues segment of the chain will not form an alpha helix at pH 7.0 but it ll take helical confirmation below its pKR value

B. Long block of Lys residues segment of the chain will not form an alpha helix at pH 7.0 but it ll take helical confirmation above its pKR value

C. Long block of Ala residues segment of the chain will not form an alpha helix at pH 7.0 but it ll take helical confirmation below its pKR value

D. Histidine side chain remain uncharged over pH range 3-6

TLS Online TPP Program

#Question id: 742

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the following

Conformation

Phi

Psi

Omega

A. Alpha helix

I. -57

P. -47

X. 180

B. B sheet

II. -135

Q. +135

Y. 0

C. Polyproline I

III. -83

R. +158

D. Polyproline II

IV. -78

S. +149

TLS Online TPP Program

#Question id: 743

#Unit 1. Molecules and their Interaction Relevant to Biology

Glycophorin, an integral membrane protein, has a single transmembrane alpha helix. Which of the following idealized hydropathy plots most likely represents the transmembrane nature of glycophorin?

TLS Online TPP Program

#Question id: 744

#Unit 1. Molecules and their Interaction Relevant to Biology

In a DNA molecule, deoxyribonucleotides are joined into a polymer by the covalent linkage of a phosphate group. The covalent link termed as:

TLS Online TPP Program

#Question id: 745

#Unit 1. Molecules and their Interaction Relevant to Biology

The structure of RNA differs from that of DNA, as RNA contains: