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TLS Online TPP Program

#Question id: 4295

Regulating iron levels in the human body is critical. Many proteins use iron as a cofactor, including the oxygen transport proteins hemoglobin and myoglobin. Consistent with the important role of iron in oxygen transport and energy production, a shortage of iron in the human body (called anemia) results in an overall feeling of weakness. On the other hand, excess iron is toxic to cells and can contribute to liver damage, heart failure, and diabetes. The iron-binding protein Ferritin is the major regulator of iron levels in the human body. Which of the following are INCORRECT regarding ferritin?

A. Ferritin translation is regulated by iron-binding proteins called iron regulatory proteins

B. The levels of transferrin, transferrin receptor, are also crucial to cellular iron homeostasis

C. Aconitase regulates synthesis of these three proteins is regulated in response to iron availability

D. apoaconitase, is actually IRE that has ability to bind to specific sequences in the mRNAs for the transferrin receptor and ferritin, thus regulating protein synthesis at the translational level.

E. IRE binding to mRNA increases synthesis of ferritin many folds.

#Unit 3. Fundamental Processes

  1. A only   

  2. B & C 

  3. E only  

  4. C, D & E

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TLS Online TPP Program

#Question id: 14982

#Unit 2. Cellular Organization

A very important function of the Golgi apparatus and endoplasmic reticulum is the synthesis of another organelle, the lysosome. This organelle is found in a variety of organisms such as—
1.Protozoa 
2. Some algae
3. Fungi
4. Plants 
5. Animals
In which of the above organisms lysosome is not found.
TLS Online TPP Program

#Question id: 14983

#Unit 2. Cellular Organization

A network of intermediate filaments, called the nuclear lamina, lies against the inner surface of the envelope and supports it. Which structure usually is associated with the inner membrane
TLS Online TPP Program

#Question id: 14984

#Unit 2. Cellular Organization

Just beneath the plasma membrane  many protozoa and some algae have a different external, rigid layer of components. The structure is called as
TLS Online TPP Program

#Question id: 14985

#Unit 4. Cell Communication and Cell Signaling

Neutrophills containing granules which have protease, protease inhibitors, for example
a) α-1 antitrypsin – regulation of proteases
b) Defensin – Direct harm to pathogen
c) Elastase –  Tissue remodelling
d) MBP – basophil degranulation
TLS Online TPP Program

#Question id: 14986

#Unit 4. Cell Communication and Cell Signaling

Which of the following characteristics of granulocyte is correct?
TLS Online TPP Program

#Question id: 14987

#Unit 4. Cell Communication and Cell Signaling

Which type of cell contains variety of proteins with distinct function; some damage pathogens directly, some regulate trafficking and activity of other WBCs, including lymphocytes, and some contribute to the remodelling of tissue at the site of infection?