TLS Online TPP Program

#Question id: 4350


Portions of the DNA sequences of normal and mutant b-globin genes are shown. The most plausible explanation for why the indicated mutation (changing an A to a G) results in the disease b-thalassemia is that the mutation

#Unit 3. Fundamental Processes
  1. changes the amino acid specified by the codon of which the altered base is part

  2. generates a recognition site for a restriction enzyme, so the gene is cut in two

  3. creates a new splice site, so that a portion of the intron is not removed

  4. results in an increase in the transcription of the b-globin gene