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TLS Online TPP Program

#Question id: 4371

Which statement is not true about the TATA box?

#Unit 3. Fundamental Processes

  1. The TBP portion of the general transcription factor TFIID binds to the TATA box forming a molecular clamp.

  2. It is located about 19-27 bp upstream from the transcription start site of class II genes.

  3. Its sequence is highly conserved among all species.

  4. This region of DNA is more easily unwound to an open complex than other general sections of DNA.

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TLS Online TPP Program

#Question id: 1274

#Unit 4. Cell Communication and Cell Signaling

Which of the following are included as functions of the extracellular matrix?

a. supporting differentiation               b. synthesis of procollagen

c. binding growth hormones               d. filtering
TLS Online TPP Program

#Question id: 17807

#Unit 8. Inheritance Biology

In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. What is the probability that a child will be albino if: Both parents are non-albino members of Generation 2?
TLS Online TPP Program

#Question id: 886

#Unit 1. Molecules and their Interaction Relevant to Biology

An experiment of Anfinsen on ribonuclease A (RNase A) showed that proteins can be denatured reversibly by 2-mercaptoethanol and 8 M urea. The protein must therefore renature spontaneously;

a) Remove mercaptoethanol and then removal of the urea

b) Removal of the mercaptoethanol allows the protein to re-form disulfide bonds in the presence of oxygen and then removal of the urea

c) Removal of the denaturant (urea) and reductant (mercaptoethanol) allows the protein to renature and re-form disulfide bonds in the absence of oxygen

d) Adding a small amount of mercaptoethanol to the scrambled protein in the absence of O2 catalyzes its conversion to the active enzyme

Which one of the following steps will leads to regaining of the full activity of ribonuclease A (RNase A)
TLS Online TPP Program

#Question id: 24235

#Unit 4. Cell Communication and Cell Signaling

In cultured cells, which of the following mutation in the EC5 domain of CDHR3 increases the cell-surface expression of CDHR3 and the binding and replication of RV-C?
TLS Online TPP Program

#Question id: 11087

#Unit 7. System Physiology – Animal

Which of the following oxygen-hemoglobin dissociation curves corresponds to normal blood (red line) and blood containing carbon monoxide (green line)?