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TLS Online TPP Program
#Question id: 15302
#Unit 5. Developmental Biology
FOXP1 is a transcription factor which stimulate the production of Oct4 and Nanog and establish pluripotency. Which of the following statements are correct regarding to the mechanism of alternative splicing of FOXP1.
A. There are two isoforms of the FoxP1 protein, One is the product of an mRNA spliced to include a particular exon, 18b, while the other splicing variant carries exon 18a.
B. When alternative splicing generates a form including exon 18b in place of 18a, the resulting isoform (FOXP1-ES) binds to a different DNA sequence and thus controls expression of a different set of genes.
C. The protein encoded by the exon 18b– carrying mRNA is called FOXP1-ES it fails to stimulate expression of OCT4 and NANOG and instead actives genes that promote differentiation.
D. The exon 18a– containing form encodes FOXP1 itself, and this has the opposite effect: this activates genes that promote dedifferentiation, and thus stimulates iPS cell formation.
TLS Online TPP Program
#Question id: 10823
#Unit 10. Ecological Principles
Which of the following statements about symbiotic relationships is true?
TLS Online TPP Program
#Question id: 541
#Unit 1. Molecules and their Interaction Relevant to Biology
The overall △G for glycolysis is -72 kJ/mol in erythrocytes. Which statement below is true?
A) The value of △G0ʹ is also -72 kJ/mol since the cytosol pH is close to 7.
B) The free energy of glycolysis is found as the sum of the standard free energy changes for
the individual pathway reactions.
C) The negative sign of △G shows that this pathway will proceed toward product (pyruvate) under normal cellular conditions.
TLS Online TPP Program
#Question id: 13086
#Unit 13. Methods in Biology
Which group of VNTRs are tandem are frequently distributed in all eukaryotic genomes (except yeast) examined so far. They show a large, stable 'polymorphism due to variation in the number of repeat units and are almost 'ideal as molecular markers for genome mapping.
TLS Online TPP Program
#Question id: 19295
#Unit 13. Methods in Biology
in genomic library To avoid ligation of separate DNA fragments, which of the enzyme is used?