During initial transcription, the active center of RNA polymerase is translocated forward relative to the DNA template and synthesizes short transcripts before aborting, then repeats this cycle until it escapes the promoter. Three models have been proposed to account for this;

i. Polymerase moves along the DNA.

ii. The front part of the enzyme moves along the DNA, but because of a flexible region within the enzyme, the back part of the enzyme can remain stationary at the promoter.

iii. The enzyme remains stationary and pulls the DNA into itself.

#Question id: 2236

#Unit 2. Cellular Organization

The partition coefficient K, the equilibrium constant for partitioning between oil and water, for butyric acid is about 10^–2, and for 1,4-butanediol it is about 10^–4.  You add liposomes containing only water to a solution with an initial concentration of 1 mM butyric acid and 100 mM 1,4-butanediol outside the liposomes.  What is the relative rate of diffusion of the two substances into the liposome interior?

#Question id: 2237

#Unit 2. Cellular Organization

Glucose enters erythrocytes via a GLUT-1 uniporter. As the levels of glucose in the bloodstream decrease between meals, what happens to the glucose in the cells?

#Question id: 2238

#Unit 2. Cellular Organization

Consider the transport of glucose into an erythrocyte by facilitated diffusion.  When the glucose concentrations are 5 mM on the outside and 0.1 mM on the inside, the free-energy change for glucose uptake into the cell is:  (These values may be of use to you:  R = 8.315 J/mol·K; T = 298 K; 9 (Faraday constant) = 96,480 J/V; N = 6.022×10²³ /mol.)

#Question id: 2239

#Unit 2. Cellular Organization

Consider the transport of K+ from the blood (where its concentration is about 4 mM) into an erythrocyte that contains 150 mM K+.  The transmembrane potential is about 60 mV, inside negative relative to outside.  The free-energy change for this transport process is:  (These values may be of use to you:  R = 8.315 J/mol.K; T = 298 K; 9 (Faraday constant) = 96,480 J/V; N = 6.022×10²³ /mol.)

#Question id: 2240

#Unit 2. Cellular Organization

 In which of the following cases is energy NOT needed for transmembrane transport?

a. Lysine moves into the cell against its concentration gradient via the Na+/lysine symporter.

b. Potassium ions (K+) move out of the cell down the K+ concentration gradient via potassium channels.

c. Glucose moves into the cell down its concentration gradient via a glucose uniporter.

d. Sodium ions (Na+) move out of the cell down the Na+ concentration gradient via sodium channels.

Which of the following are correct?

#Question id: 2241

#Unit 2. Cellular Organization

Which of the following statement(s) is (are) true of V-class proton pumps?