TLS Online TPP Program

#Question id: 4460


During initial transcription, the active center of RNA polymerase is translocated forward relative to the DNA template and synthesizes short transcripts before aborting, then repeats this cycle until it escapes the promoter. Three models have been proposed to account for this;

i. Polymerase moves along the DNA.

ii. The front part of the enzyme moves along the DNA, but because of a flexible region within the enzyme, the back part of the enzyme can remain stationary at the promoter.

iii. The enzyme remains stationary and pulls the DNA into itself.

#Unit 3. Fundamental Processes
  1. Transient excursion, Inchworming and Scrunching

  2. Scrunching, Transient excursion and Inchworming

  3. Inchworming, Transient excursion and Scrunching

  4. Inchworming, Scrunching and Transient excursion