TLS Online TPP Program

#Question id: 4484


Match General Transcription Factors with their functions;

    i. TAFs

 A. Appears to regulate the binding of TBP to DNA. It does this using an inhibitory flap that binds to the DNA-binding surface of TBP, another example of molecular mimicry. This flap must be displaced for TBP to bind TATA.

  ii. TFIIB

B. Insert into the RNA-exit channel and active center cleft of Pol II in a manner analogous to the sigma region 3/4 linker in the bacterial case.

  iii. TFIIH

 C.  As an ATP-driven translocator of double-stranded DNA.

   iv. TFIIF

D. This two-subunit (in humans) factor associates with Pol II and is recruited to the promoter together with that enzyme.

#Unit 3. Fundamental Processes
  1. i-A, ii-B, iii-C, iv-D

  2. i-B, ii-A, iii-C, iv-D

  3. i-D, ii-C, iii-B, iv-A

  4. i-A, ii-C, iii-B, iv-D