TLS Online TPP Program

#Question id: 4489


HSP70 gene from Drosophila. This gene, activated by heat shock, is controlled by two activators GAGA binding factor and HSF,In response to heat shock, HSF binds to specific sites at the promoter and recruits a kinase, P-TEFb (positive transcription elongation factor). What is the proper mechanism of pausing and release of Pol II ?

#Unit 3. Fundamental Processes
  1. Second phosphorylation on Serine5 is achieved through recruitment of the kinase P-TEFb

  2. P-TEFb is part of a super elongation complex, which releases paused Pol II from the proximal promoter.

  3. A strong acidic activator like Gal4 is able to recruit PTEFb/SEC along with the rest of the machinery

  4. B and C Only

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TLS Online TPP Program

#Question id: 1203

#Unit 4. Cell Communication and Cell Signaling

People who suffer from thyroid adenomas have constitutively activated G proteins in some cells of the thyroid gland. Tumor cells not only secrete copious quantities of thyroid hormones but also divide and grow excessively. Based on these observations, in what kind(s) of signal transduction pathways do the mutant G proteins participate?

TLS Online TPP Program

#Question id: 3668

#Unit 3. Fundamental Processes

In most plasmids, the genes for proteins required for replication are located very close to the ______________ at which their gene are transcribed.

TLS Online TPP Program

#Question id: 15147

#Unit 8. Inheritance Biology

You have isolated a set of five yeast mutants that form dark red colonies instead of the usual white colonies of wild-type yeast. You cross each of the mutants to a wild-type haploid strain and obtain the results shown below;
you cross each haploid mutant strain to a different haploid mutant of the opposite mating type. From the results shown below deduce as much as you can about which mutations lie in the same gene. Clearly state any remaining ambiguities and suggest some general ways that the ambiguities might be resolved
a) That mutants 1 and 3 form one complementation group and are mutations in the same gene (gene A) 
b) That mutations 2 and 5 form a second complementation group and are mutations in a second gene (gene B).
c) That mutations 3 and 5 form a second complementation group and are mutations in a second gene (gene B).
d) The first ambiguity is whether mutant 4 has a mutation in gene A or B, or whether it represents a unique gene.
Which of the following is the correct prediction about mutants?

TLS Online TPP Program

#Question id: 10398

#Unit 6. System Physiology – Plant

Which of the following phytochromes shows very few responses due to their highly regulated transcriptional and translational level?

TLS Online TPP Program

#Question id: 3353

#Unit 11. Evolution and Behavior