Pol I transcribes the human rRNA genes, the promoter for the rRNA gene comprises two parts: the core element and the UCE (upstream control element), for initiation there are two factors-

TLS Online TPP Program

#Question id: 24235

#Unit 4. Cell Communication and Cell Signaling

In cultured cells, which of the following mutation in the EC5 domain of CDHR3 increases the cell-surface expression of CDHR3 and the binding and replication of RV-C?

TLS Online TPP Program

#Question id: 24236

#Unit 4. Cell Communication and Cell Signaling

Which of the following protein suppresses the expression of E-cadherin during epithelial-to-mesenchymal transition?

TLS Online TPP Program

#Question id: 24237

#Unit 4. Cell Communication and Cell Signaling

What are the two major components of the extracellular matrix?

TLS Online TPP Program

#Question id: 24238

#Unit 4. Cell Communication and Cell Signaling

Which of the following does not exist as the major class of ECM molecules?

TLS Online TPP Program

#Question id: 24239

#Unit 4. Cell Communication and Cell Signaling

Integrins binds to their ligand which consist of

TLS Online TPP Program

#Question id: 24245

#Unit 4. Cell Communication and Cell Signaling

Following statements are regarding to Integrins receptors;

a. Integrins are the principal receptors used by animal cells to bind to the extracellular matrix. 

b. Integrins function as transmembrane linkers (integrators) between the extracellular matrix and the actin cytoskeleton. 

c. An integrin molecule is composed of four covalently associated transmembrane glycoprotein subunits called α2 and β2.

d. Integrins bind extracellular matrix (ECM) glycoproteins, Laminins, Collagens, Fibronectin and Vitronectin.

Which of the following statements are incorrect?