Mig1 recruits a “repressing complex” containing the Tup1 protein. This complex is recruited by many yeast DNA-binding proteins that repress transcription, including the alpha2 protein involved in controlling the mating-type specific. Tup1 also has counterparts in mammalian cells, choose correct mechanisms have been proposed to explain the repressing effect of Tup1.

I-Tup1 acts on nucleosomes either through recruiting histone deacetylases and/or by positioning a nucleosome at or near the transcription start site.

II-Tup1 interacts directly with the transcriptional machinery at the promoter and inhibits initiation.

#Question id: 5051

#Unit 5. Developmental Biology

fter the 8-cell stage, the mammalian embryo develops an outer layer (which becomes the fetal portion of the placenta), and an inner cell mass that generates all the cells of embryo. The cells of the inner cell mass are thus said to be-

#Question id: 5052

#Unit 5. Developmental Biology

cell populations within each germ layer expand and differentiate, resident stem cells are maintained within these developing tissues and function to generate cell types with restricted specificity for the tissue in which they reside. these stem cells are-

#Question id: 5053

#Unit 5. Developmental Biology

Local cell signaling is carried out via membrane receptors that bind to proteins in the extracellular matrix (ECM) or directly to receptors from a neighboring cell in a process called as-

#Question id: 5054

#Unit 5. Developmental Biology

when one group of cells changing the behavior of an adjacent set of cells, thereby causing them to change their shape, mitotic rate, or cell fate. This kind of interaction at close range between two or more cells or tissues of different histories and properties is called as-

#Question id: 5055

#Unit 5. Developmental Biology

There are at least two components to every inductive interaction-

#Question id: 5056

#Unit 5. Developmental Biology

Cells of the responding tissue must have both a receptor protein for the inducing factor and the ability to respond to the signal. The ability to respond to a specific inductive signal is called as