TLS Online TPP Program

#Question id: 4553


The NtrC protein (nitrogen regulatory protein C)—stimulates transcription of the glnA gene, this protein is an activator of σ54-RNA polymerase. Which of the following given characteristics about this protein is incorrect?

#Unit 3. Fundamental Processes
  1. NtrC is a dimeric protein, in turn, is regulated by a protein kinase called NtrB

  2. In response to high levels of glutamine, NtrB phosphorylates dimeric NtrC, enhancer-bound phosphorylated NtrC then stimulates the σ54-polymerase and initiate transcription

  3. NtrC has an ATPase activity

  4. Mutants with an NtrC that is defective in ATP hydrolysis are invariably defective in stimulating the σ54-RNA polymerase to melt the DNA strands at the transcription start site