#Question id: 4095
#Unit 3. Fundamental Processes
Many eukaryotic genes contain a large number of exons. Correct splicing of such genes requires that neighboring exons be ligated to one another; if they are not, exons will be left out. One early proposal suggested that the splicing machinery bound to a splice site at one end of an intron and scanned through the intron to find the splice site at the other end. Such a scanning mechanism would guarantee that an exon was never skipped. This hypothesis was tested with one minigene with a duplicated 3ʹ splice site. Find diagram of the products you expect from minigene if the splicing machinery binds to a 3ʹ splice site and scans toward a 5ʹ splice site.
#Question id: 30113
#Unit 1. Molecules and their Interaction Relevant to Biology
#Question id: 31080
#Unit 4. Cell Communication and Cell Signaling
#Question id: 4406
#Unit 3. Fundamental Processes
An electrophoretic mobility shift assay (EMSA) was conducted to check for the binding of TFIIB to a segment of a DNA promoter region. Which of the following approaches could be used to confirm that TFIIB is indeed binding?
#Question id: 4252
#Unit 3. Fundamental Processes
Which of the following DNA mutations is most likely to damage the protein it specifies?