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TLS Online TPP Program
#Question id: 28795
#Unit 2. Cellular Organization
There are two major classes of actin-nucleating proteins:
I- Formins
II- Arp2/3 complex
a) nucleates the assembly of branched actin networks
b) landing site for profilin–ATP–G-actin
c) nucleate the assembly of unbranched filaments
Match the correct statements with ANPs-
TLS Online TPP Program
#Question id: 28796
#Unit 2. Cellular Organization
Formin family members have two adjacent domains such as;
I- FH1
II- FH2
a) form a nucleate filament assembly
b) rich in proline
c) form a dimer
d) landing site for profilin–ATP–G-actin
e) assembly of unbranched filaments
Match the correct statements with given formin family domain;
TLS Online TPP Program
#Question id: 28797
#Unit 2. Cellular Organization
Formins are activated by___
TLS Online TPP Program
#Question id: 28798
#Unit 2. Cellular Organization
To nucleate the assembly of branched actin filaments, Arp2/3 needs to be activated by___
a) Formins protein
b) nucleation promoting factor (NPF)
c) actin-nucleating proteins (ANP)
d) Act A protein
TLS Online TPP Program
#Question id: 28799
#Unit 2. Cellular Organization
Arp2/3 needs to be activated by interacting with a nucleation promoting factor (NPF). Although there are many different NPFs, The major NPF family is characterized by the presence of a region called___
TLS Online TPP Program
#Question id: 28800
#Unit 2. Cellular Organization
Which type of signal is require to the activation of WASp, these signal input is called coincidence detection?
a) surface a protein ActA
b) regulatory phospholipid PIP2
c) small GTP-binding protein Rac1
d) small GTP-binding protein Cdc42