TLS Online TPP Program
More Questions
TLS Online TPP Program
#Question id: 18227
#Unit 8. Inheritance Biology
You are conducting genetic linkage studies of an autosomal dominant disease. You are focused on two SSR markers that may be linked to each other and to the disease. Here is a family in which some individuals are affected:
Calculate LOD scores for linkage at θ = 0.1 between the disease and SSR62
TLS Online TPP Program
#Question id: 18228
#Unit 8. Inheritance Biology
You are conducting genetic linkage studies of an autosomal dominant disease. You are focused on two SSR markers that may be linked to each other and to the disease. Here is a family in which some individuals are affected:
Calculate LOD scores for linkage at θ = 0.1 between the disease and SSR93?
TLS Online TPP Program
#Question id: 18229
#Unit 8. Inheritance Biology
You are conducting genetic linkage studies of an autosomal dominant disease. You are focused on two SSR markers that may be linked to each other and to the disease. Here is a family in which some individuals are affected:
Calculate LOD scores for linkage at θ = 0.1 between SSR62 and SSR93
TLS Online TPP Program
#Question id: 19107
#Unit 8. Inheritance Biology
Assume that mating is random. First, consider an autosomal recessive disease that is usually lethal in childhood, and that has an incidence among newborns of 1/3000. Perhaps the explanation for the incidence of the disease is heterozygote advantage. How large would this heterozygote advantage have to be (assuming the mutation rate is negligible)?
TLS Online TPP Program
#Question id: 19111
#Unit 8. Inheritance Biology
If the frequency of PKU among newborns is approximately 1/10,000 (when the parents are unrelated). What is the risk of a child with PKU if the parents are uncle and niece?
TLS Online TPP Program
#Question id: 19112
#Unit 8. Inheritance Biology
the frequency of PKU among newborns is approximately 1/10,000 (when the parents are unrelated). What is the risk of a child with PKU if the parents are second cousins?