TLS Online TPP Program

#Question id: 5145


Doris Taylor’s research group used detergents to remove all the cells from a cadaveric rat heart, which left behind the natural extracellular matrix. Proteins such as fibronectin, collagen, and laminin held together the rest of the extracellular matrix and maintained the intricate shape of the heart. The researchers then infused this extracellular matrix scaffold with cardiomyocyte progenitor cells. Surprisingly, these cells differentiated and organized into a functionally contracting “recellularized” heart. The behavior of extracellular matrix scaffold can promote the differentiation and rebuilding of a beating heart is analogous to which of the interactions?

#Unit 5. Developmental Biology
  1. Instructive interaction

  2. Permissive interaction

  3. Both A and B

  4. Neither A nor B