TLS Online TPP Program

#Question id: 5203


The biggest problem with the shotgun technique is its tendency to underestimate the size of the genome. Which of the following might best account for this?

#Unit 11. Evolution and Behavior
  1. skipping some of the clones to be sequenced

  2. missing some of the overlapping regions of the clones

  3. missing some duplicated sequences

  4. having some of the clones die during the experiment and therefore not be represented