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TLS Online TPP Program

#Question id: 28042

Thermodynamic measurements indicate that native proteins are only marginally stable under physiological conditions, The free energy required to denature them is ∼0.4 kJ∙mol−1 per amino acid residue so which of the following is true for so a fully folded 100-residue protein

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. To denature them only 40 kJ.mol−1 is required, which is equal to the breaking of one hydrogen bond
  2. To denature them only 40 kJ.mol−1 is required, which is equal to the breaking of two hydrogen bond
  3. To denature them only 40 kJ.mol−1 is required, which is equal to the breaking of three hydrogen bond
  4. To denature them only 40 kJ.mol−1 is required, which is equal to the breaking of four hydrogen bond
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TLS Online TPP Program

#Question id: 31379

#Unit 5. Developmental Biology

The cadherin catenin complex is extremely important during compaction from a morula to the blastula. Transition of early embryonic cells into a blastula differed depending on the presence or absence of calcium ions. In addition, an investigator blocked the expression of β-catenin using vivo morpholinos to detect its effect simultaneously on compaction. Which one of the following conditions will lead to the most successful transition of the morula into the blastula?
TLS Online TPP Program

#Question id: 31380

#Unit 2. Cellular Organization

If you were to remove the ER retrieval signal from protein disulfide isomerase (PDI), which is normally a soluble resident of the ER lumen, where would you expect the modified PDI to be located?
TLS Online TPP Program

#Question id: 31381

#Unit 13. Methods in Biology

Patch clamping can be used to measure the conductance properties of individual ion channels. How can patch clamping be used to determine whether the gene coding for a putative K⁺ channel actually codes for a K⁺ or a Na⁺ channel?
TLS Online TPP Program

#Question id: 31382

#Unit 4. Cell Communication and Cell Signaling

The activation of PI 3-kinase leads to the activation of a kinase, known as:
TLS Online TPP Program

#Question id: 31383

#Unit 7. System Physiology – Animal

The metabolic rate is least affected by an increase in the plasma level of:
TLS Online TPP Program

#Question id: 31384

#Unit 5. Developmental Biology

In drosophila, the third thoracic segment is transformed into another second thoracic segment due to: