TLS Online TPP Program

#Question id: 552


Which of the following is true of the binding energy derived from enzyme-substrate interactions?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. It cannot provide enough energy to explain the large rate accelerations brought about by enzymes.

  2. It is sometimes used to hold two substrates in the optimal orientation for reaction.

  3. It is the result of covalent bonds formed between enzyme and substrate.

  4. Most of it is derived from covalent bonds between enzyme and substrate.

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TLS Online TPP Program

#Question id: 30110

#Unit 1. Molecules and their Interaction Relevant to Biology

The ribose phosphate group of purine nucleotide is taken from which compound?

TLS Online TPP Program

#Question id: 30111

#Unit 1. Molecules and their Interaction Relevant to Biology

What is the source of the C-2 during the de novo biosynthesis of pyrimidines?

TLS Online TPP Program

#Question id: 30112

#Unit 1. Molecules and their Interaction Relevant to Biology

With respect to the de novo synthesis of nucleotides, which one of the following statements is INCORRECT?

TLS Online TPP Program

#Question id: 30113

#Unit 1. Molecules and their Interaction Relevant to Biology

Aspartate (Asp) is an amino acid with the structure NH2-CH(CH2-COOH)COOH. Given below are biosynthetic processes occurring in cells:
A. protein synthesis
B. de novo synthesis of inosine monophosphate and orotic acid
C. synthesis of adenosine monophosphate from inosine monophosphate
D. glutathione synthesis

Which one of the following options correctly represents all the biosynthetic process( es) wherein Asp is involved as a precursor?

TLS Online TPP Program

#Question id: 30114

#Unit 1. Molecules and their Interaction Relevant to Biology

In the case of monoclonal antibody production by hybridoma technology, myeloma cells used lack the enzyme hypxanthine - guanine phosphoriboxyl transferase(HGPRT) such that fused cells can only survive when selected on hypoxanthine-aminopterinthymdine (HAT). What is the role of aminopterin in this medium?

TLS Online TPP Program

#Question id: 30115

#Unit 1. Molecules and their Interaction Relevant to Biology

The antibacterial trimethoprim is an inhibitor of