TLS Online TPP Program

#Question id: 28354


The following statements were made regarding the patterning of anterior-posterior body plan of Drosophila:

A. Mutant bicoid mRNA that leads to the deletion of head and thorax

B. bicoid mutant phenotype expressed  two telson phenotype

C. the Bicoid protein activates the zygotic expression of the hunchback gene

D. the bicoid mRNA is represses the hunchback mRNA

Which one of the following options represents all correct statements as made above?

#Unit 5. Developmental Biology
  1. a and c only
  2.  b, c and d
  3. a, b and c
  4. c and d only
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TLS Online TPP Program

#Question id: 1520

#Unit 1. Structure and Function of Biomolecules

Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.

A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.

B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.

C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.

D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.

Which of the following statements are correct?

TLS Online TPP Program

#Question id: 27941

#Unit 1. Structure and Function of Biomolecules

Some of the following statement are made regarding the Enzymes of glycolysis along with their Coenzyme (s) or Cofactor (s) and Inhibitor (s)

a. Phosphoglucoisomerase having Mg2+ as Cofactor and can be inhibited by 2-deoxyglucose 6-phosphate
b. Aldolase having Zn2+ as Cofactor, can be inhibited by Chelating agents
c. Enolase having Mg, Mn22+ Cd2 as Cofactor, can be inhibited by Fluoride + phosphate
d. Phosphofructokinase having NAD as Coenzyme can be inhibited by Iodoacetate
Which of the following is correct

TLS Online TPP Program

#Question id: 27942

#Unit 1. Structure and Function of Biomolecules

Glycolytic enzymes along with them their class is mentioned  
(1) Phosphoglucoisomerase, Phosphotriose isomerase, Phosphoglycerate mutase belongs to Isomerases 
(2) Hexokinase, Phosphofructokinase, Phosphoglycerate kinase, Pyruvate kinase belongs to Transferases 
(3) Aldolase, Enolase belongs to Lysases 
(4) Glyceraldehyde 3-phosphate dehydrogenase belongs to Oxidoreductases

Which of the following is correct

TLS Online TPP Program

#Question id: 27943

#Unit 1. Structure and Function of Biomolecules

Which of the following reaction is catalyzes by enolase during Glycolysis

TLS Online TPP Program

#Question id: 27944

#Unit 1. Structure and Function of Biomolecules

Which one of the following is not the component of Co-A

TLS Online TPP Program

#Question id: 27945

#Unit 1. Structure and Function of Biomolecules

Which of the following statements is true regarding the payoff phase of glycolysis

a. Each molecule of glyceraldehyde 3-phosphate is oxidized and phosphorylated by ATP to form 1,3-bisphosphoglycerate 

b. Each molecule of glyceraldehyde 3-phosphate is oxidized and phosphorylated by inorganic phosphate to form 1,3-bisphosphoglycerate

c. Oxidative phosphorylation of 3-Phosphoglycerate produces one NADH

d. Oxidative phosphorylation of glyceraldehyde 3-phosphate, produces one NADH