#Question id: 1520
#Unit 1. Structure and Function of Biomolecules
Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.
A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.
B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.
C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.
D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.
Which of the following statements are correct?
#Question id: 27941
#Unit 1. Structure and Function of Biomolecules
#Question id: 27942
#Unit 1. Structure and Function of Biomolecules
#Question id: 27943
#Unit 1. Structure and Function of Biomolecules
Which of the following reaction is catalyzes by enolase during Glycolysis
#Question id: 27944
#Unit 1. Structure and Function of Biomolecules
Which one of the following is not the component of Co-A
#Question id: 27945
#Unit 1. Structure and Function of Biomolecules
Which of the following statements is true regarding the payoff phase of glycolysis
a. Each molecule of glyceraldehyde 3-phosphate is oxidized and phosphorylated by ATP to form 1,3-bisphosphoglycerate
b. Each molecule of glyceraldehyde 3-phosphate is oxidized and phosphorylated by inorganic phosphate to form 1,3-bisphosphoglycerate
c. Oxidative phosphorylation of 3-Phosphoglycerate produces one NADH
d. Oxidative phosphorylation of glyceraldehyde 3-phosphate, produces one NADH
