TLS Online TPP Program

#Question id: 28578


Sox9 and Sry also act to block the ovary-forming pathway, by  blocking__

#Unit 5. Developmental Biology
  1. Wnt
  2.  GSK3
  3.  DPP
  4. β-catenin
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TLS Online TPP Program

#Question id: 16777

#Unit 13. Methods in Biology

What is the formula for the median of Grouped data? 

TLS Online TPP Program

#Question id: 28216

#Unit 5. Developmental Biology

The cell retain stem cell niche and maintained their proliferative properties is referred to as___

TLS Online TPP Program

#Question id: 2909

#Unit 2. Cellular Organization

The DNA can be labeled and used to probe a microarray, yielding a map of genomic sequences to which those particular nucleosomes bind. Because microarrays are often referred to as chips, this technique is called a ChIP-chip experiment. This experiment is designed to reveal the genomic DNA sequences to which a particular histone variant binds. 

I. Chromatin is isolated from the cells and digested briefly with micrococcal nuclease (MNase).

II. A histone variant with an epitope tag is introduced into a particular cell type, where it is incorporated into nucleosomes.

III. The DNA bound by nucleosomes is protected from digestion, but the linker DNA is cleaved, releasing segments of DNA bound to one or two nucleosomes.

IV. The pattern of hybridization on the microarray reveals the DNA sequences bound by the nucleosomes with the histone variant.

V. Antibody is added, and the nucleosomes containing the epitope-tagged histone variant are selectively precipitated.

VI. The DNA in these nucleosomes is extracted from the precipitate, labeled, and used to probe a microarray representing all or part of the genomic sequences of that particular cell type.

 Arrange the following statements in the correct order in which they are done.

TLS Online TPP Program

#Question id: 6951

#Unit 5. Developmental Biology

In chick development, the cell movement during gastrulation is called:

TLS Online TPP Program

#Question id: 28478

#Unit 5. Developmental Biology

 Select the correct statements about these transcriptional factors-sox2, oct4 and nanog ?
a) these transcriptional factors activating those genes required to maintain totipotency in embryonic stem cells
b) these transcriptional factors activating those genes required to maintain pluripotency in embryonic stem cells
c) these transcriptional factors repressing those genes whose products would lead to differentiation