TLS Online TPP Program

#Question id: 28760


Pex5 is a receptor which binds with peroxisomal-targeting sequence proteins in the cytosol that protein targeted into the peroxisomal matrix by forming a multimeric complex with the Pex14 receptor located on the peroxisomal membrane. After assembly, the matrix protein dissociates from Pex5 and Pex5 is then returned to the cytosol by which process?

#Unit 2. Cellular Organization
  1. Pex5 ubiquitinylation by the membrane proteins Pex1 and Pex6, followed by ATP-dependent removal from the membrane by the AAA-ATPase proteins Pex2, Pex10, and Pex12

  2. Modification of membrane-bound Pex5 by methylation, Pex1 and Pex6 recognize methylation Pex5 and use the energy from ATP hydrolysis

  3. Pex5 ubiquitinylation by the membrane proteins Pex2, Pex10, and Pex12, followed by ATP-dependent removal from the membrane by the AAA-ATPase proteins Pex1 and Pex6
  4. Pex5 phosphorylation by the membrane proteins Pex19, followed by removal from the membrane by the proteins Pex6 and Pex7 spontaneously