Autophagy occurs in the following sequence of steps___

a) Nucleation of autophagosome formation by ATG9

b) Digestion of the inner membrane and the luminal contents of the autophagosome.

c) Fusion of the autophagosome with lysosomes, catalyzed by SNAREs.

d) Induction by inhibition of mTOR complex 1

e) Closure of the membrane cup to form autophagosome

#Question id: 2440

#Unit 2. Cellular Organization

Microtubule assembly in vitro requires

a. ATP.                                                           

b. a threshold (critical) concentration of tubulin.

c. warming the solution to 37°C.                   

d. microtubule-associated proteins.         

e. GTP.

#Question id: 2441

#Unit 2. Cellular Organization

Which of the following statement(s) is (are) true of microtubule assembly?

a. GDP-tubulin normally assembles into microtubules.

b. Microtubule (-) ends grow faster than microtubule (+) ends.

c. Tubulin subunits assemble to form a protofilament.

d. Microtubules consist of multiple protofilaments.

e. Microtubules with a GTP cap will shorten.

#Question id: 2442

#Unit 2. Cellular Organization

The drug colchicine acts to

a. promote microtubule assembly.     

b. inhibit microtubule assembly.

c. sever microtubules.                        

d. block cell division.

e. cap microtubule ends.

#Question id: 2443

#Unit 2. Cellular Organization

Microtubule-associated proteins

a. typically co-localize with microtubules inside cells.

b. are divided into two types: those that stabilize microtubules and those that destabilize microtubules.

c. typically co-purify with microtubules.                  

d. are similar to α- and β-tubulin.

#Question id: 2444

#Unit 2. Cellular Organization

Kinesin I moves vesicles

#Question id: 2445

#Unit 2. Cellular Organization

All members of the kinesin family of motor proteins