In the Palomino horses color is determined by three alleles at a single locus; C+/C+(light chestnut), C+/Ccr (Palomino), Ccr/Ccr (cremello). Chestnut is dominant over Palomino and cremello, and Palomino is dominant over cremello (C+/C+> C+/Ccr> Ccr/Ccr). What will be expected phenotypes and ratios of offspring produced by the C+C+/CcrCcr X C+Ccr/CcrCcr crosses?

#Question id: 1399

#Unit 4. Cell Communication and Cell Signaling

Loss-of-function mutations in which of the following genes typifies colorectal carcinomas?

a. myc              b. K-ras                       c. p53              d. APC

#Question id: 1400

#Unit 4. Cell Communication and Cell Signaling

Which property is shared by malignant tumor cells and transformed cells in culture?

a. reduced growth factor requirement                        b. attachment-dependent growth

c. loss of actin microfilaments                                    d. altered morphology

#Question id: 1401

#Unit 4. Cell Communication and Cell Signaling

Which of the following are proto-oncogenes?

a. fos               b. myc             c. p53              d. ras               e. Rb

#Question id: 1402

#Unit 4. Cell Communication and Cell Signaling

Which of the following oncoproteins possess(es) protein kinase activity?

#Question id: 1403

#Unit 4. Cell Communication and Cell Signaling

Tumor-suppressor genes encode proteins with which of the following functions?

a. growth-promoting               b. growth-arresting                  c. pro-apoptotic

d. anti-apoptotic                      e. DNA repair

#Question id: 1404

#Unit 4. Cell Communication and Cell Signaling

Which of the following are transcription factors?